hgsc.bcm.eduBCM-HGSC | Baylor College of Medicine Human Genome Sequencing Center

") ") Baylor College of Medicine Human Genome Sequencing Center HomePeople Funding News Contact Us Visiting HGSC Careers Postdoctoral Associate- Genomics Projects Clinical Lab eMERGE HeartCare KidsCanSeq Study RIGHT10K Study TMC-CZI Project Cancer Genomics The Cancer Genome Atlas Project (TCGA) Intracranial germ cell tumors Pancreaticobiliary and duodenal tumors Polycythemia vera Human Genomics Charcot-Marie-Tooth Project CHARGE Consortium eMERGE Genomic Variation Genomics and Space Medicine (Space Omics) GREGoR Human Genome Project Ion Channel Project SNP Discovery Somatic Mosaicism Across Human Tissues (SMaHT) Trans-Omics for Precision Medicine (TopMed) Microbial Genomics Microbial Projects A. apis A. castellani Neff B. pumilus F036B B. pumilus SAFR-032 D. crinitum OH494 D. discoideum AX4 E. coli DH10B E. faecalis OG1 F. nucleatum ATCC10953 F. nucleatum ATCC23726 F. tularensis MI001730 F. tularensis OR96246 F. tularensis OSU18 F. tularensis RC503 Moraxella bovis Epp63 M. haemolytica PHL213 Paenibacillus larvae P. stewartii P. violaceum P6 R. typhi S. aureus MRSA USA300 S. aureus MSSA S. iniae Texas Medical Center Genomic Center for Infectious Diseases (TMC GCID) Microbiome Data Release Policy Comparative Non-human primates Baboon Black and white colobus Chimpanzee Drill Gibbon Marmoset Mouse lemur Orangutan Owl monkey Rhesus monkey Sifaka lemur Sooty mangabey Other Mammals Armadillo Bovine Hyrax Kangaroo Rat Megabat Mouse Peromyscus Rat Sheep Wallaby Y Chromosome Marine Mammals Dolphin Killer whale Reptiles Adder Arthropods i5K Pilot Asian long-horned beetle Bark scorpion Bed bug Brown marmorated stink bug Brown recluse spider Bull-headed dung beetle Caddisfly Colorado potato beetle Common house spider Emerald ash borer Eurytemora affinis German cockroach Glassy-Winged Sharpshooter Hackberry petiole gall psyllid Hrabe’s jumping bristletail Hyalella azteca Mayfly Mediterranean fruit fly Milkweed bug Parasitic wasp: T. pretiosum Parasitic wasp: C. floridanum Parasitic wood wasp: O. abietinus Scarce Chaser Sheep blowfly Silvestri’s Northern Forcepstail Turnip sawfly Velvet worm Water strider Western black widow spider Western flower thrips Aphid Bees Bumble Bee Dwarf Honey Bee Honey Bee Drosophila D. melanogaster D. pseudoobscura Library Construction DGRP DGRP Lines modEncode Black Fly Butterfly Centipede Hessian Fly Mite Parasitic Wasp Red flour beetle Sand Fly Tobacco Hornworm Other Invertebrates Acorn Worm Cuttlefish Sea Urchin Publications Software Atlas2 ATLAS GapFill Atlas-Link Atlas Whole Genome Assembly Suite Bang bcm-ace-plots Cassandra CBT++ CoCa DRAGEN ERIS ExCID Report Honey Jelly MegaDot Mercury Parliament2 Princess SimPed Sniffles2 SNP Tools SVCollector SVhound xAtlas Resources FTP Site FTP Site Help Conditions of use HGSC Intranet Glossary Menu Genetic variation passed down through generations may influence cancer development Researchers at BCM’s Dan L Duncan Comprehensive Cancer Center and Human Genome Sequencing Center investigated the extent to which germline or inherited structural variation (SV) influence gene expression in human cancers. Read more Using generative AI assistant to interpret pharmacogenetic test results Investigators at Baylor’s HGSC are studying whether an artificial intelligence (AI) assistant could be beneficial in answering questions about genetic test results for patients and physicians. Read more Genetic germline variations influence expression of cancer cell genes Research by BCM’s Dan L Duncan Comprehensive Cancer Center and HGSC shows that specific germline structural variations represent potential candidates for cancer genetic testing. The findings are published in the journal Cell Reports Medicine. Read more Study finds ancestry-driven disparities in pathogenic variation A study led by BCM-HGSC investigators reveals new insights to the frequency of pathogenic variation among different ancestry groups in a cohort of nearly 100,000 of the All of Us participants. Read more Primate genome sequencing reveals insight into evolution, biodiversity and applications for human health A new investigation published in a series of studies in a special issue of Science analyzed the genomes of 233 nonhuman primate species and revealed key features of primate evolution, human disease and biodiversity conservation. Read more Baylor College of Medicine receives NIH funding to study somatic mosaicism NIH Common Fund program called Somatic Mosaicism across Human Tissues (SMaHT) Network awarded BCM researchers grants totaling more than $17.8 million to develop tools cataloging extent of somatic mosaicism in different cell types, tissues and life stages. Read more Human Genome Sequencing Center Clinical Lab The HGSC Clinical Laboratory (HGSC-CL) is the CAP/CLIA certified molecular diagnostic laboratory operating within the Human Genome Sequencing Center at Baylor College of Medicine. With a commitment to improving health care through genomic testing, HGSC-CL offers clinical testing services in support of large-scale clinical sequencing efforts. Learn more Texas Medical Center Genomic Center for Infectious Diseases The Texas Medical Center Genomic Center for Infectious Diseases (TMC GCID) is the collaborative effort of a multidisciplinary, integrated team of basic and physician scientists at three institutions — Baylor College of Medicine, The University of Texas Health Science Center at Houston (UTHealth) School of Public Health, and The University of Texas MD Anderson Cancer Center. The TMC GCID harnesses decades of experience in genomic sequencing, renowned clinical expertise and the use of novel ex vivo models of human intestinal and pulmonary function to create a platform for large scale genomics-based interrogation of host-mucosal pathogen interactions in the context of human tissues. Learn more BCM-HGSC Long Read Sequencing Laboratory The BCM-HGSC has been a leading institution in the development of cost effective, large-scale sequencing methods across a multitude of sequencing platforms, testing more than 250,000 samples. Our current instrumentation includes the Pacific Biosciences Sequel II and the Oxford Nanopore Technologies PromethION, and we are closely engaged with each of these platforms to test improvements to sequencing chemistry and software including early access to new protocols. Given the large capacity of these platforms, long read sequencing opportunities are available to those interested. Learn more Long Read Sequencing Seminar Series The Human Genome Sequencing Center at Baylor College of Medicine hosts quarterly virtual seminars encompassing various long read sequencing technologies applied to diverse research areas. The purpose of these seminars is to provide an environment to learn more about these technologies and how the scientific community is using these platforms in research and clinical environments. › Learn more Primate genomes studies published in Science A new investigation led by researchers at Baylor College of Medicine’s Human Genome Sequencing Center, the Institute of Evolutionary Biology and Pompeu Fabra University in Barcelona, Spain, and Illumina, Inc. analyzed the genomes of 233 nonhuman primate species and revealed key features of primate evolution, human disease and biodiversity conservation. The findings are published in a series of studies in a special issue of the journal Science . › Read the special issue of Science › Read announcement from Baylor College of Medicine Human Genome Sequencing Center awarded a grant from National Institute of Standards and Technology (NIST) The Baylor College of Medicine Human Genome Sequencing Center (BCM-HGSC) was recently awarded a grant by the National Institute of Standards and Technology (NIST) . The Genome in a Bottle (GIAB) consortium led by NIST routinely develops reference datasets for technology and method standardizations within and across entities. Principal Investigators Drs. Harsha Doddapaneni and Fritz Sedlazeck , who are each...