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") Skip to main content Baylor College of Medicine Human Genome Sequencing Center Home About Us Funding Minority Diversity G/GREAT Program PGET Program Application forms Careers Assistant Professor Bioinformatics Programmer I Postdoctoral Associate Programmer Analyst Research Assistant I Research Assistant I Senior Research Administration Associate News Contact Us Faculty Visiting HGSC Projects Clinical Lab HeartCare KidsCanSeq Study RIGHT10K Study eMERGE Cancer Genomics The Cancer Genome Atlas Project (TCGA) Intracranial germ cell tumors Pancreaticobiliary and duodenal tumors Polycythemia vera Human Genomics Charcot-Marie-Tooth Project CHARGE Consortium eMERGE Genetics of Adult Intellectual Disability Research Study Genomic Variation Human Genome Project Ion Channel Project SNP Discovery Microbial Genomics Microbial Projects A. apis A. castellani Neff B. pumilus F036B B. pumilus SAFR-032 D. crinitum OH494 D. discoideum AX4 E. coli DH10B E. faecalis OG1 F. nucleatum ATCC10953 F. nucleatum ATCC23726 F. tularensis MI001730 F. tularensis OR96246 F. tularensis OSU18 F. tularensis RC503 Moraxella bovis Epp63 M. haemolytica PHL213 Paenibacillus larvae P. stewartii P. violaceum P6 R. typhi S. aureus MRSA USA300 S. aureus MSSA S. iniae Texas Medical Center Genomic Center for Infectious Diseases (TMC GCID) Microbiome Data Release Policy Non-human primates Baboon Black and white colobus Chimpanzee Drill Gibbon Marmoset Mouse lemur Orangutan Owl monkey Rhesus monkey Sifaka lemur Sooty mangabey Other Mammals Armadillo Bovine Hyrax Kangaroo Rat Megabat Mouse Peromyscus Rat Sheep Wallaby Y Chromosome Marine Mammals Dolphin Killer whale Reptiles Adder Arthropods i5K Pilot Asian long-horned beetle Bark scorpion Bed bug Brown marmorated stink bug Brown recluse spider Bull-headed dung beetle Caddisfly Colorado potato beetle Common house spider Emerald ash borer Eurytemora affinis German cockroach Glassy-Winged Sharpshooter Hackberry petiole gall psyllid Hrabe's jumping bristletail Hyalella azteca Mayfly Mediterranean fruit fly Milkweed bug Parasitic wasp: T. pretiosum Parasitic wasp: C. floridanum Parasitic wood wasp: O. abietinus Scarce Chaser Sheep blowfly Silvestri's Northern Forcepstail Turnip sawfly Velvet worm Water strider Western black widow spider Western flower thrips Aphid Bees Bumble Bee Dwarf Honey Bee Honey Bee Drosophila D. melanogaster D. pseudoobscura Library Construction DGRP DGRP Lines modEncode Black Fly Butterfly Centipede Hessian Fly Mite Parasitic Wasp Red flour beetle Sand Fly Tobacco Hornworm Other Invertebrates Acorn Worm Cuttlefish Sea Urchin Publications Software Atlas2 ATLAS GapFill Atlas-Link Atlas Whole Genome Assembly Suite Bang bcm-ace-plots Cassandra CBT++ ERIS ExCID Report Honey Jelly MegaDot Mercury SimPed SNP Tools Resources FTP Site FTP Site Help Conditions of use HGSC Intranet Library BAC Clones Protocols: Sequencing Library Construction Glossary Menu Human Genome Sequencing Center acquires new sequencer The Baylor College of Medicine Human Genome Sequencing Center recently was awarded an NIH grant for acquisition of the Pacific Biosciences Sequel II DNA sequencing instrument. Read more HeartCare study tests genetic risk of cardiovascular disease Researchers at Baylor’s Human Genome Sequencing Center are working with cardiologists to determine patients’ genetic risk factors for cardiovascular disease, the leading cause of death for men and women in the United States. Read more Connecting gene mutations, rare genetic diseases Investigators at the Human Genome Sequencing Center have developed new approaches for large-scale analysis of Mendelian disorders. Read more Study builds roadmap for collecting, sequencing genetic data Results of a four-year NIH study to harmonize and standardize clinical genetic reporting have been published in the American Journal of Human Genetics. Read more Grant funds mucosal infection research NIH grant will fund research to study mucosal infection through the use of genomics and organoid model systems – cell-derived, in vitro 3D organ models that enable the study of biological processes. Read more Distinct stages in infant microbiome development identified In the largest clinical microbiome study in infants reported, researchers explored the sequence of microbial colonization in the infant gut and found distinct stages of development in the microbiome. Read more Human Genome Sequencing Center Clinical Lab The HGSC Clinical Laboratory (HGSC-CL) is the CAP/CLIA certified molecular diagnostic laboratory operating within the Human Genome Sequencing Center at Baylor College of Medicine. With a commitment to improving health care through genomic testing, HGSC-CL offers clinical testing services in support of large-scale clinical sequencing efforts. Learn more Texas Medical Center Genomic Center for Infectious Diseases The Texas Medical Center Genomic Center for Infectious Diseases (TMC GCID) is the collaborative effort of a multidisciplinary, integrated team of basic and physician scientists at three institutions — Baylor College of Medicine, The University of Texas Health Science Center at Houston (UTHealth) School of Public Health, and The University of Texas MD Anderson Cancer Center. The TMC GCID harnesses decades of experience in genomic sequencing, renowned clinical expertise and the use of novel ex vivo models of human intestinal and pulmonary function to create a platform for large scale genomics-based interrogation of host-mucosal pathogen interactions in the context of human tissues. Learn more COVID-19 Research Like much of the research community at this urgent time, the Baylor College of Medicine Human Genome Sequencing Center (BCM-HGSC) has turned its focus primarily toward COVID-19 testing and research. With the safety and health of the community and our personnel in mind, the BCM-HGSC is operating with staff working remotely as much as possible while a rotating lab team continues critical research on site. › Learn more about COVID-19 research at Baylor Structural Variants in the Cloud Hackathon The “Structural Variant Crying Club” is pleased to announce the next round of Structural Variants in the Cloud Hackathon teaming up with Pangenomes! Oct. 10-13, 2020, the Human Genome Sequencing Center (HGSC) at Baylor College of Medicine will host a bioinformatics hackathon and research symposium in Houston. › More info Harmonizing Clinical Sequencing and Interpretation for the eMERGE III Network A new paper available in preprint on bioRxiv describes the methods developed to harmonize genetic testing protocols linking multiple sites and investigators for the eMERGE III Network . The results mark a critical achievement toward global standardization of genetic testing by establishing protocols for different sites to harmonize the technical and interpretive aspects of sequencing tests. The integration of structured genomic results into multiple electronic health record systems by the eMERGE Network also sets the stage for clinical decision support to enable genomic medicine. Uniquely comprehensive Pan-Cancer Atlas provides essential resource A collection of 27 papers from The Cancer Genome Atlas (TCGA) consortium has been published reporting on the integrated project to analyze all 33 cancer types and to classify mutations and specific pathways. Many of the papers feature significant contributions from Baylor College of Medicine and its Human Genome Sequencing Center researchers. The findings from the 11,000 patient cohort data appear in Cell publications . Hybrid computational strategy for scalable whole genome data analysis In a study published in BMC Bioinformatics , researchers from Baylor College of Medicine’s Human Genome Sequencing Center, along with Oak Ridge National Laboratory , DNAnexus and the Human Genetics Center at the University of Texas Health Science Center, have developed a novel hybrid computational strategy to address the growing need for scalable, cost effective and real time varia...